Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704019 | 0.92 | LMNA (0.47) | LMNAMEN1KMT2ATDP1GPR52 | |
| SCHEMBL6240885 | 0.86 | SCN5A (0.40) | MEN1KMT2AKIF11 | |
| SCHEMBL5703830 | 0.86 | CHRNA7 (0.39) | LMNAMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5703836 | 0.79 | CHRNA7 (0.43) | LMNAMEN1KMT2ATDP1 | |
| SCHEMBL5703983 | 0.77 | MAPT (0.43) | MEN1KMT2AEPHX1POLB | |
| SCHEMBL6246482 | 0.74 | SCN5A (0.40) | LMNAKIF11 | |
| Hydroxyphenamate SCHEMBL5704281 | 0.74 | KMT2A (0.42) | LMNAMEN1KMT2ACHRM2CHRM3 | |
| Hydroxyphenamate SCHEMBL546919 | 0.74 | KMT2A (0.42) | LMNAMEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL27647644 | 0.72 | CTSK (0.43) | SMN1; SMN2 | |
| SCHEMBL5640773 | 0.70 | CHRM3 (0.44) | LMNAMEN1KMT2ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |