Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5703739 | 0.83 | ADRB3 (0.56) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5703738 | 0.83 | ADRB3 (0.49) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4584637 | 0.78 | L3MBTL1 (0.42) | ADRB3ADRB1ABCB1ADRB2APP | |
| SCHEMBL4584644 | 0.78 | L3MBTL1 (0.42) | ADRB3ADRB1ABCB1ADRB2APP | |
| SCHEMBL6269328 | 0.76 | KDM4E (0.41) | ADRB3ADRB1RAB9AADRB2 | |
| SCHEMBL2271534 | 0.76 | ABCB1 (0.61) | ABCB1 | |
| SCHEMBL6272979 | 0.74 | POLB (0.41) | NPC1RAB9A | |
| SCHEMBL4584322 | 0.71 | L3MBTL1 (0.49) | NPC1RAB9AABCB1 | |
| SCHEMBL6590093 | 0.69 | ERN1 (0.46) | ABCB1 | |
| SCHEMBL2277745 | 0.69 | PDGFRB (0.46) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |