Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590012 | 0.86 | SMN1; SMN2 (0.45) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL2271534 | 0.81 | ABCB1 (0.61) | ERN1ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL5191949 | 0.79 | ABCB1 (0.48) | ERN1ABCB1SIRT6ABCC1ALDH1A1 | |
| SCHEMBL8301315 | 0.79 | SIRT6 (0.53) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1318407 | 0.77 | HSD17B2 (0.54) | HTR7CYP4F2CYP4A11HSD17B2F2 | |
| SCHEMBL5195057 | 0.75 | SLC6A4 (0.49) | ERN1ABCB1SIRT6PDGFRBFGFR1 | |
| SCHEMBL5192816 | 0.75 | KDM4E (0.52) | ERN1ABCB1HTR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL6204581 | 0.74 | SMN1; SMN2 (0.44) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL6587082 | 0.74 | HDAC1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5192099 | 0.74 | ABCB1 (0.45) | ERN1ABCB1SIRT6PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472216-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | Axys Pharmaceuticals (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003066579-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | AXYS PHARMACEUTICALS (US) | 2003-08-14 | — | — | WO | disclosed |