Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267988 | 0.93 | CTSV (0.45) | POLBALDH1A1MEN1KMT2ACTSV | |
| SCHEMBL6272458 | 0.85 | NLRP3 (0.40) | MEN1KMT2APTPN2PTPN1PTPN6 | |
| SCHEMBL6272982 | 0.82 | POLB (0.40) | POLBALDH1A1MEN1KMT2ACTSV | |
| SCHEMBL6272984 | 0.82 | POLB (0.40) | POLBALDH1A1MEN1KMT2ACTSV | |
| SCHEMBL6274192 | 0.80 | MEN1 (0.37) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6270665 | 0.80 | LRRK2 (0.39) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6272839 | 0.79 | KMT2A (0.42) | KMT2A | |
| SCHEMBL6269313 | 0.79 | KMT2A (0.44) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6273802 | 0.79 | SIRT2 (0.41) | POLBMEN1KMT2ARAB9ALMNA | |
| SCHEMBL6271193 | 0.79 | KMT2A (0.41) | POLBMEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |