SCHEMBL5704170

SCHEMBL5704170

C#CCCC#COc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPC1 O15118 1/20 0.32
KCNA3 P22001 1/20 0.32
LTA4H P09960 1/20 0.32
TSHR P16473 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAOB P27338 1/20 0.31
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11571869 0.81 ESR2 (0.37) MEN1KMT2ALTA4HCYP1A2CYP2C19
SCHEMBL27814467 0.79 CYP3A4 (0.38) CYP3A4HSD17B10MAOB
SCHEMBL8029428 0.78 LTA4H (0.38) KCNA3LTA4HTSHRCA4
SCHEMBL10638650 0.75 MAPT (0.45) KMT2ATSHRCYP3A4HSD17B10
SCHEMBL11806143 0.74 MEN1 (0.32) MEN1KMT2ANPC1
Diphenylether SCHEMBL28238921 0.73 LTA4H (0.44) MEN1KMT2ALTA4HTSHR
SCHEMBL10534542 0.72 CHRNB2 (0.39) KCNA3LTA4HTSHRCYP1A2HSD17B10
SCHEMBL5919330 0.72 CYP1A2 (0.46) KCNA3LTA4HTSHRCYP1A2CYP3A4
SCHEMBL6558970 0.72 KCNA3 (0.41) KCNA3LTA4HTSHRCYP2C9CYP2C19
SCHEMBL9155898 0.72 TAAR1 (0.37) KCNA3LTA4HTSHRCYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101857677-B Silicon-containing alkyne aryl ether resin and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2012-12-05 CN claimed
CN-101857677-A Silicon-containing alkyne aryl ether resin and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2010-10-13 CN claimed
CN-100540573-C A kind of bimaleimide resin of using modified by benzene dipropargyl ether and preparation method thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2009-09-16 CN claimed
CN-101113187-A Bimaleimide resin modified by benzene dipropargyl ether and preparation method thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2008-01-30 CN claimed
CN-106832281-B It can room temperature sizing high-temperature resisting liquid modified bismaleimide resin and preparation method thereof 西安天运新材料科技有限公司 2018-12-18 CN disclosed
CN-106832281-A Can room temperature sizing high-temperature resisting liquid modified bismaleimide resin and preparation method thereof 西安天运新材料科技有限公司 2017-06-13 CN disclosed
CN-101857677-B Silicon-containing alkyne aryl ether resin and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2012-12-05 CN disclosed
CN-101838380-B Propargyl ether modified silicon-containing aryne resin UNIV EAST CHINA SCIENCE & TECH 2011-09-28 CN disclosed
CN-101857677-A Silicon-containing alkyne aryl ether resin and preparation method thereof UNIV EAST CHINA SCIENCE & TECH 2010-10-13 CN disclosed
CN-101838380-A Propargyl ether modified silicon-containing aryne resin UNIV EAST CHINA SCIENCE & TECH 2010-09-22 CN disclosed
CN-100540573-C A kind of bimaleimide resin of using modified by benzene dipropargyl ether and preparation method thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2009-09-16 CN disclosed
CN-100540573-C A kind of bimaleimide resin of using modified by benzene dipropargyl ether and preparation method thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2009-09-16 CN disclosed
US-4870064-A PHYTOPATHOGEN FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-26 US disclosed
US-4870064-A PHYTOPATHOGEN FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-26 US disclosed
EP-0333445-A2 Aromatic allene compounds and preparation thereof NIPPON PAINT CO., LTD. (JP) 1989-09-20 EP disclosed
EP-0257828-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-02 EP disclosed
EP-0257828-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-02 EP disclosed
CN-87103507-A The preparation of propargyl oxybenzene derivative and contain the mycocide of propargyl oxybenzene derivative 1988-01-13 CN disclosed
EP-0230773-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-05 EP disclosed
EP-0230773-A1 Dipropargyloxybenzene compounds and their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-05 EP disclosed