Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709806 | 0.85 | KCNH2 (0.44) | LTA4HTSHRLMNAKCNH2 | |
| SCHEMBL31544590 | 0.85 | KCNH2 (0.44) | LTA4HTSHRLMNAKCNH2 | |
| SCHEMBL10534542 | 0.83 | CHRNB2 (0.39) | LTA4HTP53CA4TSHRCHRNB2 | |
| SCHEMBL5704170 | 0.78 | MEN1 (0.34) | LTA4HCA4TSHRKCNA3 | |
| SCHEMBL11139403 | 0.74 | NR5A1 (0.54) | LTA4HTP53TSHRLMNA | |
| SCHEMBL9155898 | 0.74 | TAAR1 (0.37) | LTA4HCA4TSHRLMNAKCNA3 | |
| SCHEMBL6558970 | 0.74 | KCNA3 (0.41) | LTA4HCA4TSHRLMNAKCNA3 | |
| SCHEMBL5919330 | 0.74 | CYP1A2 (0.46) | LTA4HTSHRKCNA3 | |
| SCHEMBL9421959 | 0.74 | LTA4H (0.50) | LTA4HCA4TSHRLMNAKCNA3 | |
| SCHEMBL6572639 | 0.72 | LTA4H (0.42) | LTA4HTP53CA4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656008-B1 | THROMBIN RECEPTOR ANTAGONISTS | COR THERAPEUTICS INC (US) | 2000-03-15 | — | — | EP | claimed |
| CN-106243073-B | A kind of 2-H 1-benzopyran derivatives and its synthetic method | 华南理工大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-106243073-A | A kind of 2 H 1-benzopyran derivatives and synthetic methods thereof | 华南理工大学 | 2016-12-21 | — | — | CN | disclosed |