SCHEMBL5704185

SCHEMBL5704185

CC=C(B1OC(C)(C)C(C)(C)O1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 1/20 0.45
APLNR P35414 1/20 0.43
LPL P06858 2/20 0.40
LIPG Q9Y5X9 2/20 0.40
ANPEP P15144 1/20 0.36
LAP3 P28838 1/20 0.36
RECQL P46063 2/20 0.32
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
MAPT P10636 2/20 0.31
PLIN1 O60240 1/20 0.31
LMNA P02545 1/20 0.31
BCHE P06276 1/20 0.31
TNFRSF1A P19438 1/20 0.31
ACHE P22303 1/20 0.31
MAOB P27338 1/20 0.31
PLIN5 Q00G26 1/20 0.31
CYP1B1 Q16678 1/20 0.31
ABHD5 Q8WTS1 1/20 0.31
ALDH1A1 P00352 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5704180 1.00 P4HB (0.45) P4HBAPLNRLPLLIPGANPEP
SCHEMBL23233835 0.85 P4HB (0.44) P4HBAPLNRLPLLIPGRECQL
SCHEMBL6236653 0.85 P4HB (0.44) P4HBAPLNRLPLLIPGRECQL
SCHEMBL10299939 0.85 P4HB (0.41) P4HBAPLNRLPLLIPGANPEP
SCHEMBL6236642 0.85 P4HB (0.44) P4HBAPLNRLPLLIPGRECQL
SCHEMBL15375504 0.84 P4HB (0.40) P4HBAPLNRLPLLIPGANPEP
SCHEMBL15375505 0.84 P4HB (0.40) P4HBAPLNRLPLLIPGANPEP
SCHEMBL6236711 0.83 P4HB (0.46) P4HBAPLNRLPLLIPGRECQL
SCHEMBL6236708 0.83 P4HB (0.46) P4HBAPLNRLPLLIPGRECQL
SCHEMBL6236713 0.83 P4HB (0.46) P4HBAPLNRLPLLIPGRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1291347-B1 Process for preparing bisallylboranes and non-aromatic boronic acids CLARIANT PRODUKTE DEUTSCHLAND (DE) 2006-08-23 EP disclosed
US-6855848-B2 Process for preparing bisallylboranes and nonaromatic boronic acids CLARIANT GMBH (DE) 2005-02-15 US disclosed
US-6706925-B2 REACTING A DIENE WITH SODIUM BOROHYDRIDE IN THE PRESENCE OF AN OXIDANT AND IN AN INERT SOLVENT, WITH THE BORANE GENERATED IN SITU REACTING SELECTIVELY WITH THE DIENE TO FORM THE BIS(ALLYL)BORANE CLARIANT GMBH (DE) 2004-03-16 US disclosed
US-20040039233-A1 Process for preparing bisallylboranes and nonaromatic boronic acids CLARIANT GMBH 2004-02-26 US disclosed
US-20030096995-A1 Process for preparing bisallylboranes and nonaromatic boronic acids CLARIANT GMBH 2003-05-22 US disclosed
EP-1291347-A2 Process for preparing bisallylboranes and non-aromatic boronic acids Clariant GmbH (DE) 2003-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030096995-A1 Process for preparing bisallylboranes and nonaromatic boronic acids HBS1L, CBR1, RER1 P4HB 233/4885APLNR 2801/4885LPL 4875/4885
US-20040039233-A1 Process for preparing bisallylboranes and nonaromatic boronic acids HBS1L, CBR1, RER1 P4HB 233/4885APLNR 2801/4885LPL 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.