Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236642 | 1.00 | P4HB (0.44) | P4HBAKR1C1LPLLIPGALDH1A1 | |
| SCHEMBL23233835 | 1.00 | P4HB (0.44) | P4HBAKR1C1LPLLIPGALDH1A1 | |
| SCHEMBL5704185 | 0.85 | P4HB (0.45) | P4HBLPLLIPGALDH1A1TSHR | |
| SCHEMBL5704180 | 0.85 | P4HB (0.45) | P4HBLPLLIPGALDH1A1TSHR | |
| SCHEMBL19359472 | 0.83 | RAB9A (0.39) | P4HBLPLLIPGALDH1A1TSHR | |
| SCHEMBL19359471 | 0.83 | RAB9A (0.39) | P4HBLPLLIPGALDH1A1TSHR | |
| SCHEMBL19359276 | 0.80 | CYP1A2 (0.44) | P4HBLPLLIPGALDH1A1MAPT | |
| SCHEMBL19359565 | 0.80 | CYP1A2 (0.44) | P4HBLPLLIPGALDH1A1MAPT | |
| SCHEMBL10299939 | 0.79 | P4HB (0.41) | P4HBLPLLIPGAPLNR | |
| SCHEMBL5704275 | 0.79 | APLNR (0.50) | P4HBLPLLIPGALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307727-A | Piezochromic tetraphenyl vinyl compound and preparation method and application thereof | 河北科技大学 | 2021-08-27 | — | — | CN | disclosed |
| US-11008317-B2 | Triazolopyridine inhibitors of myeloperoxidase and/or EPX | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200291016-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | BRISTOL MYERS SQUIBB CO (US) | 2020-09-17 | — | — | US | disclosed |
| CN-109265475-B | Preparation method of polysubstituted aryl ethylene boronic acid pinacol ester derivative | 清华大学 | 2020-08-04 | — | — | CN | disclosed |
| EP-3307748-A1 | FRUSTRATED LEWIS PAIRS | Oxford University Innovation Limited (GB) | 2018-04-18 | — | — | EP | disclosed |
| WO-2017161145-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-21 | — | — | WO | disclosed |
| EP-2850087-B1 | BETA-BORATION OF ALKENE AND ALKYNE INTERMEDIATES | LEK PHARMACEUTICALS (SI) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016198892-A1 | FRUSTRATED LEWIS PAIRS | ISIS INNOVATION LIMITED (GB) | 2016-12-15 | — | — | WO | disclosed |
| EP-2850087-A1 | BETA-BORATION OF ALKENE AND ALKYNE INTERMEDIATES | LEK Pharmaceuticals d.d. (SI) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013150125-A1 | ß-BORATION OF ALKENE AND ALKYNE INTERMEDIATES | LEK PHARMACEUTICALS D.D. (SI) | 2013-10-10 | — | — | WO | disclosed |
| EP-2647639-A1 | ß-boration of alkene and alkyne intermediates | LEK Pharmaceuticals d.d. (SI) | 2013-10-09 | — | — | EP | disclosed |
| EP-1121365-B1 | ORGANOBORON DERIVATIVES AND PROCESS FOR COUPLING ORGANIC COMPOUNDS | COMMW SCIENT IND RES ORG (AU) | 2005-06-08 | — | — | EP | disclosed |
| US-6713566-B1 | CATALYTIC HYDROBORATION OF OLEFINIC OR ACETYLENIC FUNCTIONA-LIZED MATERIAL UNDER MILD CONDITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-30 | — | — | US | disclosed |
| EP-1121365-A4 | ORGANOBORON DERIVATIVES AND PROCESS FOR COUPLING ORGANIC COMPOUNDS | COMMW SCIENT IND RES ORG (AU) | 2002-03-06 | — | — | EP | disclosed |
| EP-1121365-A1 | ORGANOBORON DERIVATIVES AND PROCESS FOR COUPLING ORGANIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021966-A1 | ORGANOBORON DERIVATIVES AND PROCESS FOR COUPLING ORGANIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291016-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | EPX, MPO, SERPINB1 | P4HB 2237/4885AKR1C1 2675/4885LPL 148/4885 |
| US-11008317-B2 | Triazolopyridine inhibitors of myeloperoxidase and/or EPX | EPX, MPO, SERPINB1 | P4HB 2237/4885AKR1C1 2675/4885LPL 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.