Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491415 | 0.79 | TSHR (0.47) | NOTUMCYP1A2MAPTCXCR1CXCR2 | |
| SCHEMBL28908230 | 0.75 | DPP4 (0.39) | CYP3A4MAPTKMT2AP2RX7ERCC5 | |
| SCHEMBL23754038 | 0.73 | KDM4E (0.43) | CYP1A2CYP3A4MAPTCYP2C19CYP2C9 | |
| SCHEMBL11329865 | 0.72 | HTT (0.50) | NOTUMTAS1R3TAS1R1TAS1R2CYP1A2 | |
| SCHEMBL17716653 | 0.72 | ERCC5 (0.32) | ERCC5FEN1ALDH1A1MAPK1HIF1A | |
| SCHEMBL24410395 | 0.70 | MAPT (0.41) | CYP1A2CYP3A4MAPTCYP2C19KMT2A | |
| SCHEMBL18149189 | 0.69 | NOTUM (0.43) | NOTUMTAS1R3TAS1R1TAS1R2CYP1A2 | |
| SCHEMBL4422003 | 0.69 | ALDH1A1 (0.46) | NOTUMCYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL14661373 | 0.68 | P2RX7 (0.46) | CYP2C9CXCR1CXCR2P2RX7MRGPRX4 | |
| SCHEMBL9820959 | 0.68 | GSK3B (0.40) | CYP1A2CYP3A4MAPTCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319656-B1 | A NEW PROCESS FOR PREPARING A QUINOLONE-CARBOXYLIC ACID | LYNCHEM CO LTD (CN) | 2006-08-23 | — | — | EP | disclosed |
| US-6699992-B2 | REACTING M-FLUOROACETOPHENONE COMPOUND WITH ALKYL CARBONATE; REACTING ESTER OBTAINED WITH ALKYL ORTHOFORMATE AND AMINE; CYCLIZATION IN BASE | LYNCHEM CO., LTD. (CN) | 2004-03-02 | — | — | US | disclosed |
| US-20030166936-A1 | Process for preparing a quinolone-carboxylic acid | LYNCHEM CO., LTD. (CN) | 2003-09-04 | — | — | US | disclosed |
| EP-1319656-A1 | A NEW PROCESS FOR PREPARING A QUINOLONE-CARBOXYLIC ACID | Lynchem Co., Ltd. (CN) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166936-A1 | Process for preparing a quinolone-carboxylic acid | CYP4B1, QPCT, NQO2 | NOTUM 3283/4885TAS1R3 3436/4885TAS1R1 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.