SCHEMBL5704669

SCHEMBL5704669

COC(COCC(Cc1ccccc1)OC)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.43
SIGMAR1 Q99720 3/20 0.43
SLC6A4 P31645 3/20 0.43
SLC6A3 Q01959 3/20 0.43
SLC6A2 P23975 2/20 0.43
MAOA P21397 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
EPHX1 P07099 1/20 0.41
SLC18A2 Q05940 1/20 0.41
CYP2D6 P10635 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14586288 0.88 TRPA1 (0.44) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL791591 0.87 TAAR1 (0.50) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL8441498 0.81 TRPA1 (0.47) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL9546973 0.79 TAAR1 (0.48) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL2554330 0.79 TAAR1 (0.48) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL5704664 0.79 TRPA1 (0.53) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL12744032 0.79 TSHR (0.56) NPC1TACR1TSHR
SCHEMBL7896300 0.79 CTSK (0.49) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL8281057 0.78 KMT2A (0.36) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2
SCHEMBL11045387 0.78 MEN1 (0.38) TAAR1SIGMAR1SLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1682230-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES Symrise GmbH & Co. KG (DE) 2006-07-26 EP claimed
WO-2005004825-A1 4,8-DIMETHYL-7-NONEN-2-ONE AND 4,8-DIMETHYLNONAN-2-ONE USED AS PERFUMES SYMRISE GMBH & CO. KG (DE) 2005-01-20 WO claimed