Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554330 | 1.00 | TAAR1 (0.48) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL791591 | 0.87 | TAAR1 (0.50) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL11511087 | 0.86 | TAAR1 (0.46) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL25153003 | 0.85 | MAOB (0.57) | SLC6A2SIGMAR1MAOASLC6A3LAP3 | |
| SCHEMBL12569402 | 0.84 | ALDH1A1 (0.53) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL11565795 | 0.81 | ALDH1A1 (0.46) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL8441498 | 0.81 | TRPA1 (0.47) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL12847348 | 0.80 | TAAR1 (0.45) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL2554011 | 0.80 | TAAR1 (0.50) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL4405219 | 0.80 | SLC6A4 (0.58) | TAAR1SLC6A4CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543861-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |