Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007941 | 0.91 | TDP1 (0.51) | TDP1KEAP1FFAR1ALDH1A1LMNA | |
| SCHEMBL6705875 | 0.91 | HDAC1 (0.50) | TDP1FFAR1LMNAHDAC2HDAC8 | |
| SCHEMBL7398418 | 0.83 | TDP1 (0.53) | TDP1KEAP1FFAR1ALDH1A1LMNA | |
| SCHEMBL7299043 | 0.82 | MAPT (0.53) | TDP1KEAP1FFAR1ALDH1A1HDAC2 | |
| SCHEMBL14397264 | 0.82 | TDP1 (0.51) | TDP1KEAP1FFAR1ALDH1A1LMNA | |
| SCHEMBL22258219 | 0.81 | CA2 (0.38) | TDP1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL6491861 | 0.81 | HCAR2 (0.47) | TDP1KEAP1FFAR1ALDH1A1LMNA | |
| SCHEMBL10204722 | 0.80 | HCAR2 (0.50) | TDP1KEAP1FFAR1ALDH1A1LMNA | |
| SCHEMBL6425149 | 0.80 | TDP1 (0.85) | TDP1KEAP1FFAR1ALDH1A1APP | |
| SCHEMBL7937982 | 0.79 | HCAR2 (0.46) | TDP1ALDH1A1LMNAAPPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206293-B8 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | IOLTECH (FR) | 2006-08-30 | — | — | EP | claimed |
| EP-1206293-B1 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | IOLTECH (FR) | 2006-07-05 | — | — | EP | claimed |
| US-20040056371-A1 | Method of manufacturing ophthalmic lenses made from hydrophobic acrylic polymers | MEDENNIUM, INC. | 2004-03-25 | — | — | US | claimed |
| US-20040034118-A1 | Homopolymers containing stable elasticity inducing crosslinkers and ocular implants made therefrom | LIAO XIUGAO (US) | 2004-02-19 | — | — | US | claimed |
| US-20030055122-A1 | Homopolymers containing stable elasticity inducing crosslinkers and ocular implants made therefrom | LIAO XIUGAO (US) | 2003-03-20 | — | — | US | claimed |
| JP-2003507133-A | — | — | 2003-02-25 | — | — | JP | claimed |
| EP-1206293-A1 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | Medennium, Inc. (US) | 2002-05-22 | — | — | EP | claimed |
| US-6271281-B1 | INTRAOCULAR LENSE OF ACRYLATE POLYMERS | MEDENNIUM, INC. | 2001-08-07 | — | — | US | claimed |
| WO-2001013972-A1 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | MEDENNIUM, INC. (US) | 2001-03-01 | — | — | WO | claimed |
| EP-1206293-B8 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | IOLTECH (FR) | 2006-08-30 | — | — | EP | disclosed |
| EP-1206293-B1 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | IOLTECH (FR) | 2006-07-05 | — | — | EP | disclosed |
| EP-1543356-A1 | METHOD OF MANUFACTURING OPHTHALMIC LENSES MADE FROM HYDROPHOBIC ACRYLIC POLYMERS | Medennium, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| US-6780899-B2 | ACRYLIC ESTER HOMOPOLYMERS CONTAINING CHEMICAL CROSSLINKERS HAVING THE UNIQUE ABILITY TO PRODUCE STABLE ELASTICITY IN CONJUNCTION WITH OTHER UNIQUE PROPERTIES SUCH AS OPTICAL CLARITY AND HIGH REFRACTIVE INDEX | MEDENNIUM, INC. | 2004-08-24 | — | — | US | disclosed |
| WO-2004029675-A1 | METHOD OF MANUFACTURING OPHTHALMIC LENSES MADE FROM HYDROPHOBIC ACRYLIC POLYMERS | MEDENNIUM, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| US-20040056371-A1 | Method of manufacturing ophthalmic lenses made from hydrophobic acrylic polymers | MEDENNIUM, INC. | 2004-03-25 | — | — | US | disclosed |
| US-20040034118-A1 | Homopolymers containing stable elasticity inducing crosslinkers and ocular implants made therefrom | LIAO XIUGAO (US) | 2004-02-19 | — | — | US | disclosed |
| US-20030055122-A1 | Homopolymers containing stable elasticity inducing crosslinkers and ocular implants made therefrom | LIAO XIUGAO (US) | 2003-03-20 | — | — | US | disclosed |
| EP-1206293-A1 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | Medennium, Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| US-6271281-B1 | INTRAOCULAR LENSE OF ACRYLATE POLYMERS | MEDENNIUM, INC. | 2001-08-07 | — | — | US | disclosed |
| WO-2001013972-A1 | HOMOPOLYMERS CONTAINING CROSSLINKERS AND OCULAR IMPLANTS MADE THEREFROM | MEDENNIUM, INC. (US) | 2001-03-01 | — | — | WO | disclosed |