SCHEMBL5705351

SCHEMBL5705351

CN(C)c1nc(N)nc(N)c1N

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.33
NUDT1 P36639 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11511553 0.78 LMNA (0.46)
SCHEMBL5027790 0.78 USP2 (0.34)
SCHEMBL22524109 0.78 HRH4 (0.34)
SCHEMBL10952895 0.73 PTPRF (0.32) NUDT1
SCHEMBL24343387 0.73 NUDT1 (0.40) NOS1NUDT1
SCHEMBL10485127 0.73 NUDT1 (0.32) NOS1NUDT1
Hydrochloric Acid SCHEMBL6250957 0.73 KMT2A (0.39) NOS1
SCHEMBL10485006 0.72 KMT2A (0.41) NOS1
SCHEMBL22700395 0.72 CCNA2 (0.35)
SCHEMBL10502655 0.72 PTPRF (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1139989-B1 AGENT FOR COLORING KERATINACEOUS FIBERS HENKEL KGAA (DE) 2006-10-18 EP claimed
US-4575377-A Oxidation hair dyes comprising resorcinol derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-03-11 US claimed
US-4552565-A Hair dyes: diresorcyl sulphide, sulphoxide or sulphone coupling agents HENKEL KGAA (DE) 1985-11-12 US claimed
US-RE30199-E Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-01-29 US claimed
US-4003699-A Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL & CIE G.M.B.H. (DT) 1977-01-18 US claimed
EP-3512863-B1 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT ATEA PHARMACEUTICALS INC (US) 2021-12-08 EP disclosed
WO-2018013937-A1 BETA-D-2'-DEOXY-2'-ALPHA-FLUORO-2'-BETA-C-SUBSTITUTED-4'-FLUORO-N6-SUBSTITUTED-6-AMINO-2-SUBSTITUTED PURINE NUCLEOTIDES FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTION Atea Pharmaceuticals, Inc. (US) 2018-01-18 WO disclosed
EP-0309652-B1 HAIR DYE RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1991-10-09 EP disclosed
EP-0193656-B1 HAIR-DYEING COMPOSITION RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1990-04-25 EP disclosed
EP-0144740-B1 HAIR DYEING COMPOSITION Henkel Kommanditgesellschaft auf Aktien (DE) 1989-10-11 EP disclosed
US-4865620-A Hair dye composition RUETGERSWERKE AKTIENGESELLSCHAFT (DE) 1989-09-12 US disclosed
US-4838893-A AND TETRAAMINOPYRIDINES ASDEVELOPER COMPONENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-06-13 US disclosed
US-4213758-A Oxidation hair dyes based upon tetraaminopyrimidine developers and couplers therefor HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1980-07-22 US disclosed
EP-0011844-A1 Coupling components for oxidizing hair dyes, their preparation and hair dyes containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1980-06-11 EP disclosed
US-RE30199-E Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-01-29 US disclosed
US-4171203-A IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-10-16 US disclosed
US-4168953-A Oxidation hair dyes based upon tetraaminopyrimidine developers and monohydroxyindazole couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-09-25 US disclosed
EP-0002828-A2 Hair dyeing composition Henkel Kommanditgesellschaft auf Aktien (DE) 1979-07-11 EP disclosed
US-4129413-A Oxidation hair dyes based upon tetraaminopyrimidine developers and mono- and dialkyl -m- dihydroxy benzene couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1978-12-12 US disclosed
US-4003699-A Oxidation hair dyes based upon tetraaminopyrimidine developers HENKEL & CIE G.M.B.H. (DT) 1977-01-18 US disclosed