Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705351 | 0.78 | NOS1 (0.33) | — | |
| SCHEMBL18158244 | 0.77 | TSHR (0.33) | USP2KDM4EALDH1A1TSHR | |
| SCHEMBL9124873 | 0.77 | USP2 (0.33) | USP2KDM4EALDH1A1TSHR | |
| SCHEMBL11511553 | 0.76 | LMNA (0.46) | KDM4EALDH1A1 | |
| SCHEMBL6424033 | 0.76 | HSP90AB1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL10671138 | 0.76 | SMN1; SMN2 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL23761019 | 0.76 | JAK1 (0.31) | — | |
| SCHEMBL27761992 | 0.73 | CDK2 (0.38) | USP2TSHR | |
| SCHEMBL10485127 | 0.71 | NUDT1 (0.32) | — | |
| SCHEMBL24082065 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |