SCHEMBL5705390

SCHEMBL5705390

COc1cc(N)ccc1N=Nc1cccc(S(=O)(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 3/20 0.57
SENP3 Q9H4L4 2/20 0.57
SENP1 Q9P0U3 2/20 0.57
SUMO2 P61956 2/20 0.57
SUMO1 P63165 2/20 0.57
SENP7 Q9BQF6 2/20 0.57
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
MAPK1 P28482 3/20 0.53
MEN1 O00255 3/20 0.53
GAA P10253 2/20 0.53
KDM4E B2RXH2 2/20 0.53
CYP3A4 P08684 2/20 0.53
BLM P54132 2/20 0.53
CYP1A2 P05177 1/20 0.53
POLB P06746 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX12 P18054 1/20 0.53
CYP2C19 P33261 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9017464 0.86 SENP3 (0.52) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL9017465 0.86 SENP3 (0.52) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL8729266 0.86 PHLPP2 (0.62) KMT2AALDH1A1MAPTMAPK1MEN1
SCHEMBL11684539 0.85 SENP3 (0.57) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL11682791 0.85 SENP3 (0.57) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL14022705 0.84 PHLPP2 (0.57) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL11292444 0.83 PHLPP2 (0.59) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL2592806 0.83 SENP2 (0.61) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL2592804 0.83 SENP2 (0.61) SENP2SENP3SENP1SUMO2SUMO1
SCHEMBL11649428 0.82 MEN1 (0.49) KMT2AALDH1A1MAPTMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1370618-B1 AZO DYES CONTAINING A BARBITURIC ACID MOIETY, INK-JET PRINTING INKS AND PROCESSES FUJIFILM IMAGING COLORANTS LTD (GB) 2006-10-18 EP disclosed
US-6964701-B2 Azo dyes containing a barbituric acid moiety, ink-jet printing inks and processes AVECIA LIMITED (GB) 2005-11-15 US disclosed
US-20040112251-A1 Azo dyes containing a barbituric aid moiety, ink-jet printing inks and processes AVECIA INKJET LIMITED (GB) 2004-06-17 US disclosed
EP-1370618-A1 AZO DYES CONTAINING A BARBITURIC ACID MOIETY, INK-JET PRINTING INKS AND PROCESSES Avecia Limited (GB) 2003-12-17 EP disclosed
WO-2002072715-A1 AZO DYES CONTAINING A BARBITURIC ACID MOIETY, INK-JET PRINTING INKS AND PROCESSES AVECIA LIMITED (GB) 2002-09-19 WO disclosed