Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292444 | 0.92 | PHLPP2 (0.59) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 | |
| SCHEMBL5705390 | 0.86 | SENP2 (0.57) | PHLPP2PTGS2ENPP2PTGS1HSD17B10 | |
| SCHEMBL3309127 | 0.85 | PHLPP2 (0.63) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 | |
| SCHEMBL3309129 | 0.85 | PHLPP2 (0.63) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 | |
| SCHEMBL5720614 | 0.84 | MAPT (0.50) | PHLPP2PTGS2PTGS1ALDH1A1KDM4E | |
| SCHEMBL5720615 | 0.84 | MAPT (0.50) | PHLPP2PTGS2PTGS1ALDH1A1KDM4E | |
| SCHEMBL9462136 | 0.84 | PHLPP2 (0.56) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 | |
| SCHEMBL11297422 | 0.84 | PTGS2 (0.52) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 | |
| SCHEMBL19235141 | 0.84 | PHLPP2 (0.56) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 | |
| SCHEMBL9462138 | 0.84 | PHLPP2 (0.56) | PHLPP2PTGS2ENPP2RPS6KA3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837013-A | Preparation of colored melamine-formaldehyde condensation products | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-17 | — | — | US | disclosed |
| US-5624466-A | DYEING FIBERS, KNITS, NONWOVENS WITH AZO, ANTHRAQUINONE, COUMARIN, METHINE, QUINOPHTHALONE OR NITRO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |