Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 5/20 | 0.38 |
| ▸ | BCR | P11274 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705467 | 0.91 | TP53 (0.39) | CYP3A4ABL1BCRTP53GALR3 | |
| SCHEMBL5705461 | 0.89 | VNN1 (0.39) | CYP3A4ABL1BCRTP53GALR3 | |
| SCHEMBL5705522 | 0.89 | TP53 (0.38) | CYP3A4ABL1BCRTP53GALR3 | |
| SCHEMBL5705471 | 0.84 | VNN1 (0.40) | CYP3A4ABL1BCRTP53VNN1 | |
| Flufenerim SCHEMBL26581 | 0.82 | CYP3A4 (0.42) | CYP3A4ABL1BCRTP53GALR3 | |
| Flufenerim SCHEMBL29429245 | 0.82 | CYP3A4 (0.42) | CYP3A4ABL1BCRTP53GALR3 | |
| SCHEMBL5705480 | 0.81 | MAPK1 (0.50) | MAPTCNR2HTTRAB9A | |
| SCHEMBL9039253 | 0.76 | GALR3 (0.40) | TP53GALR3POLBMAPTCNR2 | |
| SCHEMBL27993030 | 0.76 | CYP3A4 (0.39) | CYP3A4ABL1BCRTP53VNN1 | |
| SCHEMBL15684873 | 0.74 | PDE2A (0.41) | TP53GALR3HTTRAB9ATTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074546-B1 | 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES | UBE INDUSTRIES (JP) | 2006-09-06 | — | — | EP | claimed |
| US-6521627-B1 | Insecticidal, acaricidal, nematocidal and fungicidal activities | UBE INDUSTRIES, LTD. (JP) | 2003-02-18 | — | — | US | claimed |
| EP-1074546-A1 | 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES | Ube Industries, Ltd. (JP) | 2001-02-07 | — | — | EP | claimed |
| EP-1074546-B1 | 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES | UBE INDUSTRIES (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-6521627-B1 | Insecticidal, acaricidal, nematocidal and fungicidal activities | UBE INDUSTRIES, LTD. (JP) | 2003-02-18 | — | — | US | disclosed |
| EP-1074546-A1 | 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES | Ube Industries, Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |