SCHEMBL5705994

SCHEMBL5705994

CCCCCCCCCOc1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.70
LTA4H P09960 2/20 0.65
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64
PLA2G4B P0C869 2/20 0.62
RARB P10826 3/20 0.59
NFKB1 P19838 1/20 0.57
NFKB2 Q00653 1/20 0.57
RELA Q04206 1/20 0.57
NPC1 O15118 1/20 0.57
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706031 0.95 LTA4H (0.65) FAAHLTA4HTP53TSHRPLA2G4B
SCHEMBL898713 0.92 TP53 (0.64) FAAHLTA4HTP53TSHRPLA2G4B
SCHEMBL5706280 0.88 FAAH (0.55) FAAHLTA4HNFKB1NFKB2RELA
SCHEMBL6575501 0.88 TP53 (0.58) FAAHLTA4HTP53TSHRPLA2G4B
SCHEMBL27309251 0.87 TP53 (0.59) FAAHTP53TSHRPLA2G4BRARB
Acetic Acid SCHEMBL29380777 0.86 LTA4H (0.68) FAAHLTA4HTP53TSHRPLA2G4B
SCHEMBL27949668 0.86 NPC1 (0.72) FAAHTP53TSHRPLA2G4BRARB
SCHEMBL7845911 0.86 NPC1 (0.72) FAAHTP53TSHRPLA2G4BRARB
SCHEMBL10524079 0.86 NPC1 (0.72) FAAHTP53TSHRPLA2G4BRARB
SCHEMBL5705987 0.86 NPC1 (0.72) FAAHTP53TSHRPLA2G4BRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed