Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706002 | 0.89 | KMT2A (0.63) | PTK2BKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL27596074 | 0.88 | KMT2A (0.44) | PTK2BKMT2AGAAKDM4EMAPT | |
| SCHEMBL28324306 | 0.87 | KMT2A (0.59) | KMT2AGAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3149726 | 0.81 | PTK2B (0.51) | PTK2BKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL11330648 | 0.80 | KMT2A (0.58) | KMT2AGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7539631 | 0.80 | HPGD (0.64) | PTK2BKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL1975083 | 0.80 | HPGD (0.51) | PTK2BKMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL10786907 | 0.79 | KMT2A (0.56) | KMT2AGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL689023 | 0.79 | ESR1 (0.62) | KMT2AGAAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5706048 | 0.79 | SLC6A3 (0.58) | PTK2BKMT2AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115792-B1 | WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS | GEN ELECTRIC (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1115792-A1 | WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2001-07-18 | — | — | EP | disclosed |
| US-6143839-A | THERMOPLASTIC ARYLATE POLYMER COMPRISING UNITS DERIVED FROM A RESORCINOL OR ALKYLRESORCINOL ISOPHTHALATE-TEREPHTHALATE IMPROVES COLOR STABILITY OR GLOSS RETENTION OF THE POLYCARBONATE; ARTICLES MADE FROM THE BLEND | GENERAL ELECTRIC COMPANY (US) | 2000-11-07 | — | — | US | disclosed |
| WO-2000015718-A1 | WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |