SCHEMBL5706240

SCHEMBL5706240

CCOC(=O)c1ccc(C(=O)Oc2ccccc2Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
ESR1 P03372 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
ESR2 Q92731 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CYP1A2 P05177 3/20 0.51
CYP3A4 P08684 2/20 0.51
LMNA P02545 1/20 0.51
MAOA P21397 1/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPT P10636 5/20 0.50
ALDH1A1 P00352 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706148 0.87 CA12 (0.46) SMN1; SMN2CA12CA1CA2ESR1
SCHEMBL5706248 0.87 HPGD (0.53) SMN1; SMN2LMNAMEN1KMT2AMAPT
SCHEMBL5706143 0.85 ESR1 (0.56) SMN1; SMN2ESR1ESR2CYP1A2LMNA
Ethyl Benzoate SCHEMBL11224121 0.85 SMN1; SMN2 (0.59) SMN1; SMN2CA12CA1CA2ESR1
SCHEMBL5706089 0.85 L3MBTL1 (0.55) LMNAMAOAMEN1KMT2AMAPT
SCHEMBL5706131 0.84 TSHR (0.66) ESR1ESR2MAPTALDH1A1NPSR1
SCHEMBL6813788 0.83 TSHR (0.62) SMN1; SMN2CA12CA1CA2ESR1
SCHEMBL5706048 0.82 SLC6A3 (0.58) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL6579460 0.82 TSHR (0.62) ESR1ESR2CYP1A2LMNAMAPT
SCHEMBL3149726 0.82 PTK2B (0.51) SMN1; SMN2ESR1ESR2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
CN-1131259-C Method for producing polycarbonate resin TEIJIN LTD (JP) 2003-12-17 CN disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
CN-1252817-A Process for producing polycarbonate resin TEIJIN LTD (JP) 2000-05-10 CN disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed