SCHEMBL5706248

SCHEMBL5706248

CCc1ccc(C(=O)Oc2ccccc2Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.53
RXRA P19793 1/20 0.53
RXRB P28702 1/20 0.53
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HDAC6 Q9UBN7 1/20 0.49
MAPT P10636 2/20 0.48
PTK2B Q14289 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 2/20 0.47
NR1I2 O75469 1/20 0.47
LMNA P02545 1/20 0.47
AHR P35869 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
LPAR1 Q92633 1/20 0.46
LPAR5 Q9H1C0 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706240 0.87 SMN1; SMN2 (0.54) HPGDRXRARXRBKMT2AALDH1A1
SCHEMBL5705979 0.86 HPGD (0.50) HPGDRXRARXRBKMT2AALDH1A1
SCHEMBL5706143 0.85 ESR1 (0.56) KMT2AALDH1A1MEN1MAPTPTK2B
SCHEMBL5706048 0.85 SLC6A3 (0.58) KMT2AMAPTPTK2BNPC1RAB9A
SCHEMBL5706089 0.84 L3MBTL1 (0.55) HPGDRXRARXRBKMT2AALDH1A1
SCHEMBL3149726 0.84 PTK2B (0.51) HPGDRXRARXRBKMT2AALDH1A1
SCHEMBL5706029 0.84 THRA (0.54) HPGDKMT2AALDH1A1MEN1NPSR1
SCHEMBL5706002 0.84 KMT2A (0.63) HPGDRXRARXRBKMT2AMEN1
SCHEMBL17859664 0.83 ALDH1A1 (0.47) RXRARXRBKMT2AALDH1A1MAPT
SCHEMBL1975083 0.83 HPGD (0.51) HPGDRXRARXRBKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1304458-C Process for preparing polycarbonate and apparatus for preparing polycarbonate GEN ELECTRIC (US) 2007-03-14 CN disclosed
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
CN-1555392-A Method for preparing polycarbonate and apparatus for preparing polycarbonate ͨ�õ�����˾ 2004-12-15 CN disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
CN-1131259-C Method for producing polycarbonate resin TEIJIN LTD (JP) 2003-12-17 CN disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
CN-1252817-A Process for producing polycarbonate resin TEIJIN LTD (JP) 2000-05-10 CN disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed