SCHEMBL5706102

SCHEMBL5706102

CCc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.57
ALDH1A1 P00352 5/20 0.57
PARP10 Q53GL7 1/20 0.56
MAPT P10636 4/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
TMPRSS15 P98073 2/20 0.54
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
KMT2A Q03164 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PKM P14618 1/20 0.53
NSD2 O96028 1/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
TSHR P16473 1/20 0.51
MEN1 O00255 2/20 0.50
TP53 P04637 1/20 0.49
HPGD P15428 2/20 0.49
THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL27731497 0.93 LMNA (0.54) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL4905240 0.93 KMT2A (0.62) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
Benzoquinone SCHEMBL28914486 0.92 RAB9A (0.50) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL12154217 0.90 ALDH1A1 (0.57) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL12154283 0.90 ALDH1A1 (0.57) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL26832415 0.90 ALDH1A1 (0.57) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL12199916 0.90 ALDH1A1 (0.57) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL3771392 0.88 KMT2A (0.56) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL11672038 0.87 ALDH1A1 (0.71) RAB9AALDH1A1PARP10MAPTSMN1; SMN2
SCHEMBL19220417 0.87 PRSS1 (0.52) RAB9AALDH1A1MAPTSMN1; SMN2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999386-B Polyaryletherketone resin containing carboxyl side group and synthesis method thereof 浙江鹏孚隆新材料有限公司 2023-06-06 CN disclosed
CN-113999386-A Polyaryletherketone resin containing carboxyl side group and synthesis method thereof 浙江鹏孚隆新材料有限公司 2022-02-01 CN disclosed
CN-109553555-B Synthesis method of 4-methyl-N-phenyl-N- (2-phenylpropyl-1-alkenyl) benzene sulfonamide compound 山东理工大学 2021-01-08 CN disclosed
CN-105492469-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2018-07-17 CN disclosed
US-8182975-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
EP-1897928-B1 Chlorofluorobenzene liquid crystal compound, liquid crystal composition and liquid crystal display device CHISSO CORP (JP) 2010-10-27 EP disclosed
US-7786122-B2 α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2010-08-31 US disclosed
US-20080248419-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20080085894-A1 ALPHA-(N-SULFONAMIDO)ACETAMIDE DERIVATIVES AS BETA-AMYLOID INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2008-04-10 US disclosed
US-7189782-B2 Thermoplastic film, thermoplastic resin composition, and phyllosilicate TEIJIN LIMITED (JP) 2007-03-13 US disclosed
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080085894-A1 ALPHA-(N-SULFONAMIDO)ACETAMIDE DERIVATIVES AS BETA-AMYLOID INHIBITORS APP, APBA1, BACE1 RAB9A 1585/4885ALDH1A1 1197/4885PARP10 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.