Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627883 | 0.88 | SERPINE1 (0.49) | CA12CA7CA1CA4ALDH1A1 | |
| SCHEMBL29366009 | 0.88 | SERPINE1 (0.49) | CA12CA7CA1CA4ALDH1A1 | |
| SCHEMBL5706147 | 0.88 | ALDH1A1 (0.53) | CA12CA7CA1CA4KDM4E | |
| SCHEMBL24949033 | 0.85 | CA12 (0.45) | CA12CA7CA1CA4ALDH1A1 | |
| SCHEMBL28410933 | 0.83 | RXRA (0.45) | CA12CA7CA1CA4ALDH1A1 | |
| SCHEMBL25966157 | 0.81 | TYMS (0.48) | CA12CA7CA1CA4HSD17B10 | |
| SCHEMBL6431511 | 0.81 | CA12 (0.54) | CA12CA7CA1CA4CA2 | |
| SCHEMBL3290858 | 0.81 | MAPT (0.51) | CA12CA7CA1CA4HSD17B10 | |
| SCHEMBL30399202 | 0.81 | MAPT (0.51) | CA12CA7CA1CA4HSD17B10 | |
| SCHEMBL11280439 | 0.80 | KDM4E (0.68) | KDM4EHSD17B10HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491884-A1 | POLYPHENYLENE ETHER-POLYARYLENE SULFIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1992-07-01 | — | — | EP | claimed |
| WO-1992001749-A1 | POLYPHENYLENE ETHER-POLYARYLENE SULFIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1992-02-06 | — | — | WO | claimed |
| US-5066719-A | Melt blending with trimellitic anhydride salicylate ester, vacuum, polyamideether copolymer compatibilizers | GENERAL ELECTRIC COMPANY (US) | 1991-11-19 | — | — | US | claimed |
| EP-0440939-A2 | Polyphenylene ether-polyamide compositions from dicarboxylate-capped polyphenylene ethers | GENERAL ELECTRIC COMPANY (US) | 1991-08-14 | — | — | EP | claimed |
| US-4988775-A | Improved heat stability for impact strength and tensile strength | GENERAL ELECTRIC COMPANY (US) | 1991-01-29 | — | — | US | claimed |
| EP-1412411-B1 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GEN ELECTRIC (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-0498283-B1 | Copolymers of dicarboxylic acids and salicylic acids | GEN ELECTRIC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0498284-B1 | Polyphenylene ether-polyamide compositions from dicarboxylate-capped polyphenylene ethers | GEN ELECTRIC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0498282-B1 | Preparation of functionalized polyphenylene ether using copolymers of dicarboxylic acids and salicylic acids | GEN ELECTRIC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0504560-A1 | Preparation of anhydride-capped polyphenylene ether in a melt process | GENERAL ELECTRIC COMPANY (US) | 1992-09-23 | — | — | EP | disclosed |
| EP-0501154-A2 | Polyphenylene ether-polyamide compositions | GENERAL ELECTRIC COMPANY (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5141999-A | PREPARATION OF ANHYDRIDE-CAPPED POLYPHENYLENE ETHER IN A MELT PROCESS | GENERAL ELECTRIC COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-5122575-A | Oxidative stability from linear anhydrides rather than cyclic ones | GENERAL ELECTRIC COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
| WO-1992001749-A1 | POLYPHENYLENE ETHER-POLYARYLENE SULFIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1992-02-06 | — | — | WO | disclosed |
| US-5066719-A | Melt blending with trimellitic anhydride salicylate ester, vacuum, polyamideether copolymer compatibilizers | GENERAL ELECTRIC COMPANY (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0440939-A2 | Polyphenylene ether-polyamide compositions from dicarboxylate-capped polyphenylene ethers | GENERAL ELECTRIC COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| EP-0440939-A2 | Polyphenylene ether-polyamide compositions from dicarboxylate-capped polyphenylene ethers | GENERAL ELECTRIC COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4988775-A | Improved heat stability for impact strength and tensile strength | GENERAL ELECTRIC COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4988775-A | Improved heat stability for impact strength and tensile strength | GENERAL ELECTRIC COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4988775-A | Improved heat stability for impact strength and tensile strength | GENERAL ELECTRIC COMPANY (US) | 1991-01-29 | — | — | US | disclosed |