Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 3/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | GGT1 | P19440 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273464 | 0.96 | KDM4E (0.64) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL30505635 | 0.96 | SLC6A3 (0.71) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL1979275 | 0.96 | SLC6A3 (0.71) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL8777320 | 0.94 | SLC6A3 (0.69) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL4846409 | 0.93 | ESR1 (0.69) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL28263594 | 0.92 | HSD17B10 (0.72) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL30343057 | 0.91 | KDM4E (0.58) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL14484254 | 0.91 | KDM4E (0.58) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL1323563 | 0.91 | KDM4E (0.61) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL11672847 | 0.88 | SLC6A3 (0.62) | KDM4EHSD17B10HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-20130035317-A1 | Di-Aspirin Derivatives | THE UNIVERISTY OF WOLVERHAMPTON (GB) | 2013-02-07 | — | — | US | disclosed |
| US-20130035317-A1 | Di-Aspirin Derivatives | THE UNIVERISTY OF WOLVERHAMPTON (GB) | 2013-02-07 | — | — | US | disclosed |
| WO-2011098839-A2 | DI-ASPIRIN DERIVATIVES | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2011-08-18 | — | — | WO | disclosed |
| EP-0052927-A2 | Stretched film structure of the poly-1,3-phenylene terephthalate type | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035317-A1 | Di-Aspirin Derivatives | SDHA, DLD, DPYD | KDM4E 2764/4885HSD17B10 987/4885HPGD 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.