SCHEMBL5706155

SCHEMBL5706155

CCOC(=O)c1ccccc1OC(=O)c1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.52
TSHR P16473 1/20 0.50
NPSR1 Q6W5P4 1/20 0.48
ELANE P08246 1/20 0.46
PRTN3 P24158 1/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HSPA1A P0DMV8 1/20 0.46
PTPN7 P35236 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
GAA P10253 1/20 0.45
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
MAPT P10636 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6813163 0.90 NPSR1 (0.56) SLC6A3TSHRNPSR1ELANEPRTN3
SCHEMBL7210223 0.88 TSHR (0.65) SLC6A3TSHRKDM4ELMNASMN1; SMN2
SCHEMBL5706020 0.86 SLC6A3 (0.69) SLC6A3TSHRKDM4ELMNASMN1; SMN2
SCHEMBL6813788 0.86 TSHR (0.62) SLC6A3TSHRKDM4ELMNASMN1; SMN2
SCHEMBL5706241 0.85 SLC6A3 (0.48) SLC6A3TSHRNPSR1ELANEPRTN3
SCHEMBL5706100 0.85 SLC6A3 (0.73) SLC6A3TSHRNPSR1ELANEPRTN3
SCHEMBL7641505 0.85 SLC6A3 (0.59) SLC6A3TSHRKDM4ELMNASMN1; SMN2
SCHEMBL5705988 0.85 MAPT (0.48) TSHRNPSR1ELANEPRTN3KDM4E
SCHEMBL8993035 0.85 SMN1; SMN2 (0.59) TSHRLMNASMN1; SMN2NPC1RAB9A
SCHEMBL6812697 0.84 TSHR (0.59) SLC6A3TSHRKDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
US-6423813-B1 FROM PHENOLIC COMPOUNDS TEIJIN LIMITED (JP) 2002-07-23 US disclosed
EP-1179556-A1 BRANCHED AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND BLOW-MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-02-13 EP disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed