SCHEMBL6812697

SCHEMBL6812697

CCOC(=O)c1ccccc1OC(=O)c1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
SLC6A3 Q01959 1/20 0.56
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
ALDH1A1 P00352 2/20 0.52
KMT2A Q03164 2/20 0.52
NOD2 Q9HC29 1/20 0.52
HSD17B10 Q99714 1/20 0.51
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
MAPT P10636 2/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7210223 0.95 TSHR (0.65) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL6813788 0.94 TSHR (0.62) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL6817469 0.91 NPC1 (0.60) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL5706020 0.91 SLC6A3 (0.69) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL7641505 0.90 SLC6A3 (0.59) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL8499592 0.90 SLC6A3 (0.68) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL6439342 0.90 SLC6A3 (0.72) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL6564035 0.90 CA12 (0.63) TSHRSLC6A3NPC1RAB9AALDH1A1
SCHEMBL9685392 0.87 SLC6A3 (0.63) SLC6A3RAB9AKMT2AHSD17B10ESR1
SCHEMBL5706055 0.87 SLC6A3 (0.56) TSHRSLC6A3NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed