Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888233 | 0.93 | CA1 (0.63) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL7592080 | 0.87 | ESR1 (0.77) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL17940713 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL10506176 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL5706155 | 0.85 | SLC6A3 (0.52) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| Benzene SCHEMBL27873122 | 0.84 | CA1 (0.76) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL12260654 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL11460865 | 0.83 | CYP19A1 (0.49) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL11460868 | 0.83 | CYP19A1 (0.49) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| Ethyl Benzoate SCHEMBL11224187 | 0.82 | LMNA (0.61) | SMN1; SMN2RAB9ANPC1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |