Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5706183 | 0.99 | TPH1 (0.44) | TPH1ALDH1A1LDHAACACBNSD2 | |
| Hydrochloric Acid SCHEMBL5706174 | 0.99 | TPH1 (0.44) | TPH1ALDH1A1LDHAACACBNSD2 | |
| SCHEMBL4648020 | 0.82 | TPH1 (0.48) | TPH1ALDH1A1ACACB | |
| SCHEMBL5109806 | 0.81 | DPP4 (0.47) | TPH1ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL6161194 | 0.81 | DPP4 (0.47) | TPH1ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4648016 | 0.81 | TPH1 (0.48) | TPH1ALDH1A1ACACB | |
| Hydrochloric Acid SCHEMBL4648024 | 0.81 | TPH1 (0.48) | TPH1ALDH1A1ACACB | |
| Hydrochloric Acid SCHEMBL5112988 | 0.80 | DPP4 (0.46) | TPH1ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5148984 | 0.80 | DPP4 (0.46) | TPH1ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7296827 | 0.80 | LDHA (0.59) | TPH1ALDH1A1LDHASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701933-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061440-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2005-07-07 | — | — | WO | disclosed |