Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | FAP | Q12884 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5109806 | 1.00 | DPP4 (0.47) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5112988 | 0.98 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5148984 | 0.98 | DPP4 (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7960935 | 0.87 | SLC7A5 (0.48) | TPH1ALDH1A1 | |
| SCHEMBL5569674 | 0.86 | DPP4 (0.48) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL14938754 | 0.86 | DPP4 (0.48) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL16060347 | 0.86 | DPP4 (0.48) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL7529709 | 0.86 | ACACB (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5569672 | 0.85 | ALDH1A1 (0.49) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL5635196 | 0.85 | DPP4 (0.47) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210335-B1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |
| US-5714497-A | EXHIBIT AFFINITY FOR BIOLOGICAL RECEPTORS OF NEUROPEPTIDE Y | SANOFI (FR) | 1998-02-03 | — | — | US | disclosed |
| US-5674890-A | HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS; PSYCHOLOGICAL DISORDERS; ANTAGONISTS OF PEPTIDE Y | SANOFI (FR) | 1997-10-07 | — | — | US | disclosed |
| US-5506258-A | EXHIBIT AFFINITY FOR THE BIOLOGICAL RECEPTORS OF NEUROPEPTIDES Y, WHICH ARE PRESENT IN THE CENTRAL AND PERIPHERAL NERVOUS SYSTEMS | ELF SANOFI (FR) | 1996-04-09 | — | — | US | disclosed |