SCHEMBL5706221

SCHEMBL5706221

C#CCOCCCS(=O)(=O)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
APP P05067 1/20 0.38
PTGS1 P23219 1/20 0.31
PDE4A P27815 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A6 P31641 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15412880 0.98 TSHR (0.50) TSHRAPPPTGS1PDE4ALMNA
SCHEMBL20514341 0.94 TSHR (0.50) TSHRAPPPTGS1PDE4ALMNA
SCHEMBL11079760 0.87 TSHR (0.45) TSHRAPPPTGS1PDE4ALMNA
SCHEMBL421993 0.79 APP (0.50) TSHRAPPPTGS1PDE4ALMNA
SCHEMBL15412165 0.79 TSHR (0.47) TSHR
SCHEMBL18071751 0.79 TSHR (0.47) TSHRLMNA
SCHEMBL15252849 0.78 TSHR (0.46) TSHRLMNACA12CA1CA2
SCHEMBL25299218 0.77 APP (0.48) TSHRAPPPTGS1PDE4ALMNA
SCHEMBL20875302 0.77 APP (0.48) APPPTGS1PDE4ALMNASLC6A6
SCHEMBL19640302 0.77 APP (0.48) APPPTGS1PDE4ALMNASLC6A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291307-B Plating bath composition and method for electroless plating of palladium 埃托特克德国有限公司 2020-02-14 CN claimed
US-10513780-B2 Plating bath composition and method for electroless plating of palladium ATOTECH DEUTSCHLAND GMBH (DE) 2019-12-24 US claimed
EP-3380649-B1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH DEUTSCHLAND GMBH (DE) 2019-10-30 EP claimed
US-20180340260-A1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) 2018-11-29 US claimed
EP-3380649-A1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH Deutschland GmbH (DE) 2018-10-03 EP claimed
WO-2022017442-A1 BIFUNCTIONAL PROTEIN DEGRADATION-TARGETED CHIMERA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF 恩瑞生物医药科技(上海)有限公司 2022-01-27 WO disclosed
US-10858747-B2 Acidic zinc and zinc nickel alloy plating bath composition and electroplating method ATOTECH DEUTSCHLAND GMBH (DE) 2020-12-08 US disclosed
CN-108291307-B Plating bath composition and method for electroless plating of palladium 埃托特克德国有限公司 2020-02-14 CN disclosed
US-10513780-B2 Plating bath composition and method for electroless plating of palladium ATOTECH DEUTSCHLAND GMBH (DE) 2019-12-24 US disclosed
EP-3380649-B1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH DEUTSCHLAND GMBH (DE) 2019-10-30 EP disclosed
CN-106661750-B Acidic zinc and Zinc-nickel alloy electroplating bath composition and electro-plating method 安美特德国有限公司 2019-01-29 CN disclosed
US-20180340260-A1 PLATING BATH COMPOSITION AND METHOD FOR ELECTROLESS PLATING OF PALLADIUM ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) 2018-11-29 US disclosed
US-9309283-B2 Prodrugs of peptide epoxy ketone protease inhibitors ONYX THERAPEUTICS, INC. (US) 2016-04-12 US disclosed
US-20140105921-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors ONYX THERAPEUTICS, INC. 2014-04-17 US disclosed
EP-1517869-B1 AIR-ENTRAINING ADMIXTURES BCD ROHSTOFFE FUER BAUCHEMIE H (AT) 2006-10-25 EP disclosed
EP-0291588-B1 SIZING AGENT KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1991-09-04 EP disclosed
EP-0224976-B1 METHOD OF SIZING PAPER KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1989-10-18 EP disclosed
US-4826570-A PARTIAL ESTER OF ALKENYL SUCCINIC ACID, PAPERMAKING KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1989-05-02 US disclosed
EP-0291588-A1 Sizing agent KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1988-11-23 EP disclosed
EP-0224976-A1 Method of sizing paper KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1987-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140105921-A1 Prodrugs of Peptide Epoxy Ketone Protease Inhibitors PREP, VIP, PEPD TSHR 3808/4885APP 127/4885PTGS1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.