SCHEMBL5706346

SCHEMBL5706346

c1ccc2cc3c(cc2c1)c1c(c2ccccc23)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
CYP1A2 P05177 3/20 0.49
LCK P06239 1/20 0.49
FYN P06241 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
MAPT P10636 1/20 0.49
ACHE P22303 1/20 0.49
SLC6A2 P23975 1/20 0.49
AHR P35869 1/20 0.49
HSD17B10 Q99714 4/20 0.42
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
HPRT1 P00492 3/20 0.40
TRPM4 Q8TD43 1/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 2/20 0.37
THRB P10828 1/20 0.37
NQO1 P15559 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10879816 0.91 ALDH1A1 (0.46) ALDH1A1CYP1A2LCKFYNADORA3
Benzo[B]Triphenylene SCHEMBL29374595 0.82 ALDH1A1 (0.58) ALDH1A1CYP1A2HSD17B10HIF1ACYP1B1
Benzo[B]Triphenylene SCHEMBL71635 0.82 ALDH1A1 (0.58) ALDH1A1CYP1A2HSD17B10HIF1ACYP1B1
Benzo[B]Triphenylene SCHEMBL29628013 0.82 ALDH1A1 (0.58) ALDH1A1CYP1A2HSD17B10HIF1ACYP1B1
SCHEMBL4855544 0.82 ALDH1A1 (0.58) ALDH1A1CYP1A2HSD17B10HIF1ACYP1B1
Benzo[B]Triphenylene SCHEMBL17537048 0.79 ALDH1A1 (0.55) ALDH1A1CYP1A2HSD17B10HIF1ACYP1B1
SCHEMBL415471 0.79 ALDH1A1 (0.55) ALDH1A1CYP1A2HSD17B10HIF1ACYP1B1
SCHEMBL711515 0.76 ALDH1A1 (0.52) ALDH1A1CYP1A2FYNMAPTACHE
SCHEMBL14877458 0.76 ALDH1A1 (0.52) ALDH1A1CYP1A2FYNMAPTACHE
SCHEMBL296990 0.76 ALDH1A1 (0.52) ALDH1A1CYP1A2FYNMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1707668-A1 CLOSED CYCLE ZERO DISCHARGE OXIDIZING PULPING PROCESS Mei, Xiuquan (CN) 2006-10-04 EP disclosed