Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845752 | 0.84 | TSHR (0.42) | PTGS2HDAC6 | |
| SCHEMBL321122 | 0.78 | TDP1 (0.39) | — | |
| SCHEMBL3149589 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL79020 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL8355942 | 0.74 | RAB9A (0.44) | ATM | |
| SCHEMBL9418157 | 0.74 | ESR1 (0.47) | — | |
| SCHEMBL7139286 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL8325832 | 0.74 | CYP1A2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL8359885 | 0.74 | MEN1 (0.42) | ATM | |
| SCHEMBL28957329 | 0.74 | CYP1A2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692101-A1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2006-08-23 | — | — | EP | claimed |
| WO-2004087644-A1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | claimed |