Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455906 | 0.83 | SLC1A2 (0.46) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL6824845 | 0.83 | SLC1A2 (0.46) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| Water SCHEMBL4794963 | 0.81 | SLC1A2 (0.45) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL9449386 | 0.81 | SLC1A1 (0.54) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL7359265 | 0.81 | SLC1A1 (0.54) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL14423585 | 0.77 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL15383208 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL2402182 | 0.76 | GRIK1 (0.44) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL22115798 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL17664953 | 0.75 | DDAH1 (0.49) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692098-A1 | ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056519-A1 | ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | WO | disclosed |