Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 5/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.45 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455906 | 1.00 | SLC1A2 (0.46) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Water SCHEMBL4794963 | 0.98 | SLC1A2 (0.45) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1514886 | 0.89 | SLC1A2 (0.49) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL27532543 | 0.89 | SLC1A2 (0.49) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL476726 | 0.89 | SLC1A2 (0.49) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL7066411 | 0.84 | SLC1A1 (0.58) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL5707302 | 0.83 | SLC7A5 (0.44) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL7781906 | 0.82 | NAAA (0.56) | SLC1A2SLC1A1GRIK1GRIK2P2RY10 | |
| SCHEMBL7918479 | 0.82 | NAAA (0.56) | SLC1A2SLC1A1GRIK1GRIK2P2RY10 | |
| SCHEMBL16124672 | 0.82 | NAAA (0.56) | SLC1A2SLC1A1GRIK1GRIK2P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |