SCHEMBL5707457

SCHEMBL5707457

CC(C)CC1(C(=O)NC2=CC=CC[CH]2)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 16/20 0.41
MME P08473 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1730663 0.88 CETP (0.56) CETPMME
SCHEMBL528758 0.88 CETP (0.51) CETPMME
SCHEMBL2994117 0.86 CETP (0.49) CETPMME
SCHEMBL5707500 0.84 CETP (0.47) CETPMME
SCHEMBL5707494 0.81 CETP (0.47) CETP
SCHEMBL5778500 0.72 LMNA (0.50) CETPMME
SCHEMBL528151 0.71 CETP (0.77) CETPMME
SCHEMBL5707503 0.70 CETP (0.47) CETPMME
SCHEMBL5707515 0.69 CETP (0.48) CETPMME
SCHEMBL5707738 0.69 CETP (0.49) CETPMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1020439-B1 CETP ACTIVITY INHIBITORS JAPAN TOBACCO INC (JP) 2006-08-30 EP claimed