Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29928336 | 0.78 | LMNA (0.50) | LMNANPSR1CETPRAB9AROCK2 | |
| SCHEMBL29530533 | 0.76 | LMNA (0.51) | LMNANPSR1RAB9AROCK2ROCK1 | |
| SCHEMBL30687001 | 0.76 | LMNA (0.51) | LMNANPSR1RAB9AROCK2ROCK1 | |
| SCHEMBL30687000 | 0.76 | LMNA (0.51) | LMNANPSR1RAB9AROCK2ROCK1 | |
| SCHEMBL1555616 | 0.76 | LMNA (0.48) | LMNANPSR1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30687009 | 0.75 | ROCK2 (0.50) | LMNANPSR1RAB9AROCK2ROCK1 | |
| SCHEMBL528151 | 0.74 | CETP (0.77) | CETPMME | |
| SCHEMBL7336412 | 0.73 | LMNA (0.45) | LMNANPSR1RAB9AMDM2EPHX1 | |
| SCHEMBL5707457 | 0.72 | CETP (0.41) | CETPMME | |
| SCHEMBL12841111 | 0.72 | CETP (0.64) | CETPRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1715862-A1 | KINASE INHIBITORS | Devgen NV (BE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082367-A1 | KINASE INHIBITORS | DEVGEN NV (BE) | 2005-09-09 | — | — | WO | disclosed |