Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707457 | 0.81 | CETP (0.41) | CETP | |
| SCHEMBL1730663 | 0.78 | CETP (0.56) | CETP | |
| SCHEMBL528758 | 0.78 | CETP (0.51) | CETP | |
| SCHEMBL2994117 | 0.76 | CETP (0.49) | CETP | |
| SCHEMBL5707500 | 0.73 | CETP (0.47) | CETP | |
| SCHEMBL8115837 | 0.71 | SMN1; SMN2 (0.35) | LMNAGAACYP3A4ALDH1A1SMN1; SMN2 | |
| Water SCHEMBL11230562 | 0.68 | CETP (0.50) | CETPP2RX7ADORA1LMNAGAA | |
| SCHEMBL5707651 | 0.67 | L3MBTL1 (0.45) | CETPADORA1LMNAGAAALDH1A1 | |
| SCHEMBL2034401 | 0.65 | CETP (0.47) | CETPP2RX7CNR1CNR2CYP3A4 | |
| SCHEMBL1524902 | 0.65 | P2RX7 (0.73) | CETPP2RX7LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020439-B1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC (JP) | 2006-08-30 | — | — | EP | claimed |