SCHEMBL5707547

SCHEMBL5707547

Cc1ccccc1C(=O)OC[C@@H]1O[C@@H](Br)[C@H](OC(=O)c2ccccc2C)[C@H]1OC(=O)c1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ANTXR2 P58335 3/20 0.46
▸ TSHR P16473 3/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ PTPN1 P18031 2/20 0.39
▸ ADRB2 P07550 2/20 0.38
▸ ADRB1 P08588 2/20 0.38
▸ ADRB3 P13945 2/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ GAPDH P04406 1/20 0.38
▸ CASP1 P29466 1/20 0.37
▸ CASP7 P55210 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ BCHE P06276 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ MAPT P10636 2/20 0.37
▸ LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707653 0.91 ANTXR2 (0.42) ANTXR2TSHRL3MBTL1MEN1KMT2A
SCHEMBL8588901 0.84 ANTXR2 (0.53) ANTXR2TSHRL3MBTL1MEN1KMT2A
SCHEMBL8588057 0.81 ANTXR2 (0.41) ANTXR2TSHRL3MBTL1MEN1KMT2A
SCHEMBL6898523 0.81 ANTXR2 (0.41) ANTXR2TSHRL3MBTL1MEN1KMT2A
SCHEMBL6380989 0.80 PTPN1 (0.55) ANTXR2TSHRL3MBTL1MEN1KMT2A
SCHEMBL5707687 0.79 USP2 (0.55) TSHRL3MBTL1MEN1KMT2APTPN1
SCHEMBL11726595 0.79 USP2 (0.55) TSHRL3MBTL1MEN1KMT2APTPN1
SCHEMBL2493929 0.79 USP2 (0.55) TSHRL3MBTL1MEN1KMT2APTPN1
SCHEMBL11061066 0.79 USP2 (0.55) TSHRL3MBTL1MEN1KMT2APTPN1
SCHEMBL14274463 0.79 USP2 (0.55) TSHRL3MBTL1MEN1KMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO. INC (JP) 2006-10-12 — — US disclosed
EP-1705181-A2 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO., INC. (JP) 2006-09-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound DCTD, DERA, HDHD5 ANTXR2 4203/4885TSHR 2062/4885L3MBTL1 586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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