SCHEMBL5707653

SCHEMBL5707653

Cc1ccccc1C(=O)OC[C@@H]1O[C@@H](Br)[C@H](Br)[C@H]1OC(=O)c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ANTXR2 P58335 3/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TSHR P16473 3/20 0.38
▸ ADRB2 P07550 2/20 0.38
▸ ADRB1 P08588 2/20 0.38
▸ ADRB3 P13945 2/20 0.38
▸ GAPDH P04406 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ CASP7 P55210 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ BCHE P06276 1/20 0.36
▸ MAPT P10636 3/20 0.36
▸ LMNA P02545 1/20 0.36
▸ PTPN1 P18031 1/20 0.36
▸ NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707547 0.91 ANTXR2 (0.46) ANTXR2L3MBTL1MEN1KMT2ATSHR
SCHEMBL8588901 0.81 ANTXR2 (0.53) ANTXR2L3MBTL1MEN1KMT2ATSHR
SCHEMBL5707553 0.80 POLB (0.51) L3MBTL1MEN1KMT2ATSHRGAPDH
SCHEMBL5707557 0.80 POLB (0.51) L3MBTL1MEN1KMT2ATSHRGAPDH
SCHEMBL6898523 0.80 ANTXR2 (0.41) ANTXR2L3MBTL1MEN1KMT2ATSHR
SCHEMBL8588057 0.80 ANTXR2 (0.41) ANTXR2L3MBTL1MEN1KMT2ATSHR
SCHEMBL6380989 0.76 PTPN1 (0.55) ANTXR2L3MBTL1MEN1KMT2ATSHR
SCHEMBL11178783 0.76 TSHR (0.46) L3MBTL1MEN1KMT2ATSHRADRB2
SCHEMBL5677495 0.72 L3MBTL1 (0.39) L3MBTL1MEN1KMT2ATSHRADRB2
SCHEMBL6842406 0.72 BCHE (0.43) L3MBTL1MEN1KMT2ATSHRADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO. INC (JP) 2006-10-12 — — US disclosed
EP-1705181-A2 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO., INC. (JP) 2006-09-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound DCTD, DERA, HDHD5 ANTXR2 4203/4885L3MBTL1 586/4885MEN1 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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