Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380973 | 0.85 | SMN1; SMN2 (0.59) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL27720018 | 0.85 | SMN1; SMN2 (0.59) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL221141 | 0.85 | SMN1; SMN2 (0.59) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL258365 | 0.81 | NOS2 (0.57) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL30821626 | 0.81 | NOS2 (0.57) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL29923727 | 0.81 | ALDH1A1 (0.59) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL632502 | 0.81 | ALDH1A1 (0.59) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL11466167 | 0.80 | NOS2 (0.56) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL29009329 | 0.80 | NOS2 (0.52) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL30735953 | 0.80 | ALDH1A1 (0.58) | NOS2SMN1; SMN2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1705227-A2 | New dyestuffs and colorants with specific carbonyl compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-09-27 | — | — | EP | claimed |
| EP-1705227-A2 | New dyestuffs and colorants with specific carbonyl compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-09-27 | — | — | EP | disclosed |