SCHEMBL5708147

SCHEMBL5708147

CCC(C)OOc1ccccc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
RECQL P46063 1/20 0.51
HSD17B10 Q99714 7/20 0.50
HPGD P15428 5/20 0.50
ALDH1A1 P00352 9/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HMGB1 P09429 1/20 0.49
TSHR P16473 1/20 0.49
GGT1 P19440 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
BLM P54132 1/20 0.49
NAPRT Q6XQN6 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HTT P42858 2/20 0.46
PTK2B Q14289 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899339 0.83 KDM4E (0.54) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL17010754 0.83 KDM4E (0.56) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL9129863 0.81 KDM4E (0.54) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL29124279 0.77 ALDH1A1 (0.54) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL29010714 0.76 KDM4E (0.63) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL9551796 0.76 KDM4E (0.49) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL4206867 0.76 KDM4E (0.55) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL10595073 0.75 PPARG (0.48) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL554352 0.75 KDM4E (0.55) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL7982231 0.74 KDM4E (0.55) KDM4EKMT2AMEN1RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1358220-B1 CATALYST OBTAINED BY PREPOLYMERIZATION OF POLYOLEFIN AND OLEFIN POLYMERIZATION METHOD USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2006-11-22 EP disclosed
US-7098285-B2 Catalyst obtained by prepolymerization of polyolefin and olefin polymerization method using the same SAMSUNG ATOFINA CO., LTD. (KR) 2006-08-29 US disclosed
EP-1301545-B1 A CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF OLEFIN POLYMERIZATION USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2006-05-31 EP disclosed
US-6884746-B2 Catalysts for olefin polymerization and method of olefin polymerization using the same SAMSUNG GENERAL CHEMICALS, CO., LTD. (KR) 2005-04-26 US disclosed
EP-1301545-A4 A CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF OLEFIN POLYMERIZATION USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2005-01-19 EP disclosed
EP-1358220-A4 CATALYST OBTAINED BY PREPOLYMERIZATION OF POLYOLEFIN AND OLEFIN POLYMERIZATION METHOD USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2004-06-09 EP disclosed
US-20040063862-A1 Catalyst obtained by prepolymerization of polyolefin and olefin polymerization method using the same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2004-04-01 US disclosed
US-20040014594-A1 Catalysts for olefin polymerization and method of olefin polymerization using the same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2004-01-22 US disclosed
EP-1358220-A1 CATALYST OBTAINED BY PREPOLYMERIZATION OF POLYOLEFIN AND OLEFIN POLYMERIZATION METHOD USING THE SAME Samsung General Chemicals Co., Ltd. (KR) 2003-11-05 EP disclosed
EP-1301545-A1 A CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF OLEFIN POLYMERIZATION USING THE SAME Samsung General Chemicals Co., Ltd. (KR) 2003-04-16 EP disclosed
WO-2002048206-A1 CATALYST OBTAINED BY PREPOLYMERIZATION OF POLYOLEFIN AND OLEFIN POLYMERIZATION METHOD USING THE SAME SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2002-06-20 WO disclosed
WO-2001098375-A1 A CATALYST FOR OLEFIN POLYMERIZATION AND METHOD OF OLEFIN POLYMERIZATION USING THE SAME SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-12-27 WO disclosed