Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836605 | 0.93 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Sebacic Acid SCHEMBL7696353 | 0.89 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL17309751 | 0.86 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL122686 | 0.84 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1899339 | 0.84 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL17309763 | 0.83 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL177388 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL5512458 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28329496 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL27447943 | 0.83 | KDM4E (0.53) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109999218-A | A kind of temperature sensitive type high intensity tissue adhesive | 西南交通大学 | 2019-07-12 | — | — | CN | claimed |
| US-9999705-B2 | Protein biomaterials and biocoacervates and methods of making and using thereof | GEL-DEL TECHNOLOGIES, INC. (US) | 2018-06-19 | — | — | US | claimed |
| US-20160158411-A1 | PROTEIN BIOMATERIALS AND BIOCOACERVATES AND METHODS OF MAKING AND USING THEREOF | PETVIVO HOLDINGS, INC. | 2016-06-09 | — | — | US | claimed |
| US-8871267-B2 | Protein matrix materials, devices and methods of making and using thereof | GEL-DEL TECHNOLOGIES, INC. (US) | 2014-10-28 | — | — | US | claimed |
| US-20120282300-A1 | PROTEIN BIOMATERIALS AND BIOCOACERVATES AND METHODS OF MAKING AND USING THEREOF | GEL-DEL TECHNOLOGIES, INC. (US) | 2012-11-08 | — | — | US | claimed |
| US-20100196478-A1 | PROTEIN MATRIX MATERIALS, DEVICES AND METHODS OF MAKING AND USING THEREOF | GEL-DEL TECHNOLOGIES, INC. (US) | 2010-08-05 | — | — | US | claimed |
| US-7662409-B2 | Biocompatible protein materials compressed with one or more biocompatible solvents to remove bulk solvent and form an interacting protein matrix material. | GEL-DEL TECHNOLOGIES, INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-20230108636-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | UNIV JOHNS HOPKINS (US) | 2023-04-06 | — | — | US | disclosed |
| EP-1713514-B1 | DRUGS AND GENE CARRIER PARTICLES THAT RAPIDLY MOVE THROUGH MUCOUS BARRIERS | UNIV JOHNS HOPKINS (US) | 2021-11-24 | — | — | EP | disclosed |
| US-20210052507-A1 | DRUGS AND GENE CARRIER PARTICLES THAT RAPIDLY MOVE THROUGH MUCOUS BARRIERS | UNIV JOHNS HOPKINS (US) | 2021-02-25 | — | — | US | disclosed |
| US-20200345864-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | THE JOHNS HOPKINS UNIVERSITY | 2020-11-05 | — | — | US | disclosed |
| CN-109999218-A | A kind of temperature sensitive type high intensity tissue adhesive | 西南交通大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-109999218-A | A kind of temperature sensitive type high intensity tissue adhesive | 西南交通大学 | 2019-07-12 | — | — | CN | disclosed |
| WO-2008030557-A2 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | JOHNS HOPKINS UNIVERSITY (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008008387-A2 | DRUG DELIVERY POLYANHYDRIDE COMPOSITION AND METHOD | BIOABSORBABLE THERAPEUTICS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| EP-1713514-A2 | DRUGS AND GENE CARRIER PARTICLES THAT RAPIDLY MOVE THROUGH MUCOUS BARRIERS | The Johns Hopkins University (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005072710-A2 | DRUGS AND GENE CARRIER PARTICLES THAT RAPIDLY MOVE THROUGH MUCOUS BARRIERS | JOHNS HOPKINS UNIVERSITY (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20030105518-A1 | Biodegradable drug delivery material for stent | DUTTA DEBASHIS (US) | 2003-06-05 | — | — | US | disclosed |
| US-20030097173-A1 | Biodegradable drug delivery material for stent | DUTTA DEBASHIS (US) | 2003-05-22 | — | — | US | disclosed |
| US-6527801-B1 | Biodegradable drug delivery material for stent | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2003-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230108636-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | SLC26A4, SLC26A3, SLC10A2 | KDM4E 4800/4885KMT2A 4568/4885MEN1 2800/4885 |
| US-20210052507-A1 | DRUGS AND GENE CARRIER PARTICLES THAT RAPIDLY MOVE THROUGH MUCOUS BARRIERS | ABCB11, ABCB1, SLC47A2 | KDM4E 4826/4885KMT2A 4727/4885MEN1 2389/4885 |
| US-20200345864-A1 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS | SLC26A4, SLC26A3, SLC10A2 | KDM4E 4800/4885KMT2A 4568/4885MEN1 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.