Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856432 | 0.85 | ALOX5 (0.61) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL2003642 | 0.85 | KMT2A (0.53) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL5335470 | 0.82 | KMT2A (0.60) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL8561986 | 0.79 | KMT2A (0.55) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL27747363 | 0.77 | KMT2A (0.53) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL9051523 | 0.77 | NPC1 (0.61) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL12642453 | 0.77 | KMT2A (0.60) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL258616 | 0.76 | CYP3A4 (0.64) | ALDH1A1MAPTALOX5PTGESNPC1 | |
| SCHEMBL417705 | 0.76 | MAPT (0.60) | HTTALDH1A1MAPTALOX5RAB9A | |
| SCHEMBL1578827 | 0.76 | SMN1; SMN2 (0.56) | HTTALDH1A1MAPTALOX5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419126-B1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIV PITTSBURGH (US) | 2006-11-02 | — | — | EP | disclosed |
| US-6806357-B1 | REACTING THE ALCOHOL AND A NUCLEOPHILE WITH AN AZODICARBOXYLATE AND A PHOSPHINE. AT LEAST ONE OF THE AZODICARBOXYLATE AND THE PHOSPHINE INCLUDES AT LEAST ONE FLUOROUS TAG | UNIVERSITY OF PITTSBURGH | 2004-10-19 | — | — | US | disclosed |
| EP-1419126-A1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIVERSITY OF PITTSBURGH (US) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003016246-A1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIVERSITY OF PITTSBURGH (US) | 2003-02-27 | — | — | WO | disclosed |