Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388876 | 0.86 | RAB9A (0.61) | ALDH1A1RAB9AMAPK1L3MBTL1MAPT | |
| SCHEMBL11686784 | 0.83 | ALDH1A1 (0.65) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL6704659 | 0.83 | KMT2A (0.50) | ALDH1A1RAB9AL3MBTL1MAPTKMT2A | |
| SCHEMBL14724028 | 0.82 | MAPT (0.53) | ALDH1A1RAB9AMAPK1L3MBTL1KCNJ1 | |
| SCHEMBL7188600 | 0.81 | MAPT (0.55) | ALDH1A1MAPK1KCNJ1KCNH2MAPT | |
| SCHEMBL11383154 | 0.81 | RAB9A (0.56) | ALDH1A1RAB9AMAPK1L3MBTL1MAPT | |
| SCHEMBL10749890 | 0.81 | RAB9A (0.56) | ALDH1A1RAB9AMAPK1L3MBTL1MAPT | |
| SCHEMBL5024676 | 0.81 | MAPT (0.52) | ALDH1A1RAB9AMAPK1L3MBTL1KCNJ1 | |
| SCHEMBL11541924 | 0.81 | ALDH1A1 (0.56) | ALDH1A1RAB9AMAPK1L3MBTL1MAPT | |
| SCHEMBL9654481 | 0.81 | RAB9A (0.56) | ALDH1A1RAB9AMAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419126-B1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIV PITTSBURGH (US) | 2006-11-02 | — | — | EP | disclosed |
| US-6806357-B1 | REACTING THE ALCOHOL AND A NUCLEOPHILE WITH AN AZODICARBOXYLATE AND A PHOSPHINE. AT LEAST ONE OF THE AZODICARBOXYLATE AND THE PHOSPHINE INCLUDES AT LEAST ONE FLUOROUS TAG | UNIVERSITY OF PITTSBURGH | 2004-10-19 | — | — | US | disclosed |