Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448708 | 0.86 | THRA (0.51) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL378767 | 0.86 | THRA (0.51) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL6647574 | 0.81 | HSP90AB1 (0.49) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL7673210 | 0.76 | MEN1 (0.39) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL1258900 | 0.76 | MEN1 (0.44) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL11083679 | 0.76 | MEN1 (0.44) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL5879457 | 0.74 | ESR1 (0.39) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL5708437 | 0.74 | CRHBP (0.37) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL4036461 | 0.73 | GPR35 (0.52) | MEN1KMT2AGPR35MAPTKDM4E | |
| SCHEMBL1530400 | 0.72 | MEN1 (0.55) | MEN1KMT2ALMNAHTTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994721-B1 | NERVE GROWTH FACTOR AS A VACCINE ADJUVANT | PROTECHTION UNLTD INC (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-0994721-A4 | NERVE GROWTH FACTOR AS A VACCINE ADJUVANT | PROTECHTION UNLTD INC (US) | 2003-08-27 | — | — | EP | disclosed |
| US-6572866-B1 | Nerve growth factor as a vaccine adjuvant | PROTECHTION UNLIMITED, INC. | 2003-06-03 | — | — | US | disclosed |
| US-20020052313-A1 | Nerve growth factor as a vaccine adjuvant | TORCIA MARIA (IT) | 2002-05-02 | — | — | US | disclosed |
| EP-0994721-A1 | NERVE GROWTH FACTOR AS A VACCINE ADJUVANT | Protechtion Unlimited, Inc. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998048832-A1 | NERVE GROWTH FACTOR AS A VACCINE ADJUVANT | PROTECHTION UNLIMITED, INC. (US) | 1998-11-05 | — | — | WO | disclosed |