Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629929 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TP53GAACYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL11625827 | 0.97 | KMT2A (0.58) | ALDH1A1TP53GAACYP3A4CYP1A2 | |
| SCHEMBL9577200 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL66632 | 0.87 | CYP3A4 (0.70) | ALDH1A1TP53GAACYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL1580080 | 0.86 | CYP3A4 (0.68) | ALDH1A1TP53GAACYP3A4KMT2A | |
| SCHEMBL9129125 | 0.85 | MEN1 (0.72) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL9129895 | 0.83 | MEN1 (0.74) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL13314764 | 0.83 | TSHR (0.61) | ALDH1A1TP53GAAKMT2AMEN1 | |
| SCHEMBL7955008 | 0.83 | ALDH1A1 (0.68) | ALDH1A1CYP3A4KMT2AMEN1PKM | |
| SCHEMBL6671584 | 0.82 | ALDH1A1 (0.79) | ALDH1A1TP53CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999209-B1 | 2-SULFAMOYLBENZOIC ACID DERIVATIVES | KAKEN PHARMA CO LTD (JP) | 2006-11-02 | — | — | EP | disclosed |
| CN-1195739-C | 2-sulfamoylbenzoic acid derivatives | KAKEN PHARMA CO LTD (JP) | 2005-04-06 | — | — | CN | disclosed |
| US-20020049228-A1 | 2-Sulfamoylbenzoic acid derivatives | KAKEN PHARMACEUTICALS | 2002-04-25 | — | — | US | disclosed |
| US-6376671-B1 | LEUKOTRIENE AND THROMBOXANE A2 ANTAGONISTIC AGENTS; ANTIALLERGIC AGENTS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6255321-B1 | ANTIALLERGENS; RESPIRATRORY SYSTEM DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| CN-1260783-A | 2-sulfamoylbenzoic acid derivatives | KAKEN PHARMA CO LTD (JP) | 2000-07-19 | — | — | CN | disclosed |
| EP-0999209-A1 | 2-SULFAMOYLBENZOIC ACID DERIVATIVES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049228-A1 | 2-Sulfamoylbenzoic acid derivatives | LTB4R2, LTB4R, CYSLTR2 | ALDH1A1 810/4885TP53 4478/4885GAA 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.