SCHEMBL7955008

SCHEMBL7955008

Cc1ccc(S(=O)(=O)NCCCCN)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.68
CA12 O43570 1/20 0.64
CA2 P00918 1/20 0.64
CA9 Q16790 1/20 0.64
ALOX15 P16050 1/20 0.62
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
HTT P42858 2/20 0.58
MBTD1 Q05BQ5 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
LMNA P02545 2/20 0.57
PKM P14618 2/20 0.56
CYP3A4 P08684 1/20 0.54
GBA1 P04062 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17599857 0.98 ALDH1A1 (0.66) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL12849347 0.98 ALDH1A1 (0.66) ALDH1A1CA12CA2CA9ALOX15
Hydrochloric Acid SCHEMBL5093423 0.97 ALDH1A1 (0.64) ALDH1A1CA12CA2CA9ALOX15
Hydrochloric Acid SCHEMBL11629317 0.97 ALDH1A1 (0.64) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL13426054 0.95 ALDH1A1 (0.62) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7628596 0.95 ALDH1A1 (0.70) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7094852 0.91 ALDH1A1 (0.79) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL8494571 0.91 ALDH1A1 (0.65) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7097551 0.89 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7093365 0.89 ALDH1A1 (0.77) ALDH1A1CA12CA2CA9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6264966-B1 DEODORANTS; THERAPY FOR ORAL DISEASES CONCAT, LTD. 2001-07-24 US disclosed
US-5556853-A THIOL PROTEASE INHIBITORS, TREATMENT OF OSTEOPOROSIS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-09-17 US disclosed
EP-0655447-A1 Epoxysuccinic acid derivatives Takeda Chemical Industries, Ltd. (JP) 1995-05-31 EP disclosed