Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946859 | 0.75 | MTOR (0.40) | KMT2APOLBSMN1; SMN2GPR27MTOR | |
| SCHEMBL2946856 | 0.75 | MTOR (0.40) | KMT2APOLBSMN1; SMN2GPR27MTOR | |
| SCHEMBL2943447 | 0.75 | KMT2A (0.36) | KMT2APOLBMAPK7SMN1; SMN2 | |
| SCHEMBL2943450 | 0.75 | KMT2A (0.36) | KMT2APOLBMAPK7SMN1; SMN2 | |
| SCHEMBL5707012 | 0.74 | DGAT1 (0.40) | KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL13234361 | 0.73 | RAB9A (0.45) | KMT2APOLBALDH1A1SMN1; SMN2MTOR | |
| SCHEMBL2944264 | 0.72 | LTA4H (0.49) | KMT2AMAPK7ALDH1A1GPR27 | |
| SCHEMBL9796364 | 0.70 | GAA (0.49) | KMT2AALDH1A1 | |
| SCHEMBL9796361 | 0.70 | GAA (0.49) | KMT2AALDH1A1 | |
| SCHEMBL9768810 | 0.67 | NAPRT (0.38) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709028-A1 | FUSED HETEROARYL DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005073217-A1 | FUSED HETEROARYL DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-11 | — | — | WO | disclosed |