SCHEMBL5708922

SCHEMBL5708922

C#CC[C@]1(n2ccc(N)nc2=O)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLG P54098 2/20 0.48
P2RY2 P41231 10/20 0.44
P2RY6 Q15077 7/20 0.44
P2RY4 P51582 6/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6038233 0.91 POLG (0.50) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL10900419 0.89 POLG (0.49) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL597307 0.87 POLG (0.49) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL886859 0.86 POLG (0.41) POLGP2RY2P2RY6P2RY4
SCHEMBL30134674 0.85 POLG (0.46) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL6141746 0.85 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL25396644 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL17215886 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL585724 0.84 POLG (0.51) POLGP2RY2P2RY6P2RY4POLB
SCHEMBL5086175 0.83 POLG (0.43) POLGP2RY2P2RY6P2RY4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116134020-A Lipid compounds comprising at least one terminal group of formula-NH-CX-A or-NH-CX-NH-A, compositions containing them and uses thereof 赛诺菲巴斯德有限公司 2023-05-16 CN disclosed
EP-1725572-A2 MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME Genovoxx GmbH (DE) 2006-11-29 EP disclosed
WO-2005044836-A2 MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME GENOVOXX GMBH (DE) 2005-05-19 WO disclosed