Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 4/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31707305 | 0.82 | MEN1 (0.42) | PNMTCD44MAOBHTR2AHTR2C | |
| SCHEMBL829355 | 0.82 | MEN1 (0.42) | PNMTCD44MAOBHTR2AHTR2C | |
| SCHEMBL29788066 | 0.78 | HTR2A (0.61) | CD274PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL329913 | 0.78 | HTR2A (0.61) | CD274PNMTHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL915156 | 0.76 | HTR2A (0.59) | CD274PNMTHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7075718 | 0.74 | HTR2A (0.58) | CD274PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL18554708 | 0.70 | CD274 (0.51) | CD274PNMTCD44MAOBHTR2A | |
| SCHEMBL6634111 | 0.70 | CHRNA7 (0.60) | HTR2AHTR2C | |
| SCHEMBL3051568 | 0.70 | CHRNA7 (0.60) | HTR2AHTR2C | |
| SCHEMBL14645815 | 0.70 | CD274 (0.56) | CD274PNMTCD44MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708999-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005070887-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2005-08-04 | — | — | WO | disclosed |